A novel SIRT1 activator E6155 improves insulin sensitivity in type 2 diabetic KKA(y) mice

Sirtuin 1 (SIRT1) is an NAD(+)-dependent protein deacetylase that plays a critical role in controlling energy metabolism, stress response and aging. Hence, enhancing SIRT1 activity could be a potential therapeutic strategy to treat metabolic diseases such as diabetes. However, pharmacological activa...

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Publicado en:Biochem Biophys Res Commun
Main Authors: Liu, Peng, Feng, Tingting, Zuo, Xuan, Wang, Xiao, Luo, Jinque, Li, Ni, Han, Xiaowan, Zhu, Ningyu, Xu, Suowen, Xu, Yanni, Jin, Zheng Gen, Si, Shuyi
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898622/
https://ncbi.nlm.nih.gov/pubmed/29524414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.03.034
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