Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis

Nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) plays an important role in the regulation of glucose homeostasis and lipid metabolism. However, current PPARγ-targeting drugs such as thiazolidinediones (TZDs) are associated with undesirable side effects. We identified a small mo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Liu, Chang, Feng, Tingting, Zhu, Ningyu, Liu, Peng, Han, Xiaowan, Chen, Minghua, Wang, Xiao, Li, Ni, Li, Yongzhen, Xu, Yanni, Si, Shuyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381330/
https://ncbi.nlm.nih.gov/pubmed/25827822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09530
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky