P-cresol and Indoxyl Sulfate Impair Osteogenic Differentiation by Triggering Mesenchymal Stem Cell Senescence

Chronic kidney disease (CKD) patients obtained high levels of uremic toxins progressively develop several complications including bone fractures. Protein-bound uremic toxins especially p-cresol and indoxyl sulfate are hardly eliminated due to their high molecular weight. Thus, the abnormality of bon...

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Dades bibliogràfiques
Publicat a:Int J Med Sci
Autors principals: Kamprom, Witchayapon, Tawonsawatruk, Tulyapruek, Mas-Oodi, Sumana, Anansilp, Korrarit, Rattanasompattikul, Manoch, Supokawej, Aungkura
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797544/
https://ncbi.nlm.nih.gov/pubmed/33437209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.48492
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