Exploration of the relationship between tumor mutation burden and immune infiltrates in colon adenocarcinoma

Background: Tumor mutation burden (TMB) was correlated with the immunotherapeutic response in various malignancies. We aimed to evaluate the TMB immune signature in colon adenocarcinoma (COAD). Methods: Gene expression profile, mutation and clinical data of COAD patients were obtained from The Cance...

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Udgivet i:Int J Med Sci
Main Authors: Ouyang, Rong, Li, Zhongzhuan, Peng, Peng, Zhang, Jinxiu, Liu, Jun, Qin, Mengbin, Huang, Jiean
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797534/
https://ncbi.nlm.nih.gov/pubmed/33437203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.51918
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