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Mucin 4 mutation is associated with tumor mutation burden and promotes antitumor immunity in colon cancer patients

At present, immunotherapy is widely used for different mismatch repair (dMMR) or highly microsatellite instability (MSI-H) colorectal cancer patients, and tumor mutation burden (TMB) is a valuable independent predictor of response to immunotherapy. However, specific gene mutations and their relation...

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Podrobná bibliografie
Vydáno v:Aging (Albany NY)
Hlavní autoři: Peng, Linglong, Li, Yang, Gu, Haitao, Xiang, Ling, Xiong, Yongfu, Wang, Rong, Zhou, He, Wang, Jijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034916/
https://ncbi.nlm.nih.gov/pubmed/33714943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202756
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