A Rare Potential Pathogenic Variant in the BDNF Gene is Found in a Brazilian Patient with Severe Childhood-Onset Obesity

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is a pro-survival factor in the brain that also regulates energy balance. BDNF loss-of-function point mutations are responsible for haploinsufficiency, causing severe early-onset obesity. Up to date, only a few studies have sequenced this gene to...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Diabetes Metab Syndr Obes
Asıl Yazarlar: da Fonseca, Ana Carolina Proença, Abreu, Gabriella de Medeiros, Palhinha, Lohanna, Zembrzuski, Verônica Marques, Campos Junior, Mario, Carneiro, João Regis Ivar, Nogueira Neto, José Firmino, Magno, Fernanda Cristina C Mattos, Rosado, Eliane Lopes, Maya-Monteiro, Clarissa Menezes, de Cabello, Giselda Maria Kalil, Cabello, Pedro Hernán, Bozza, Patricia Torres
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2021
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797284/
https://ncbi.nlm.nih.gov/pubmed/33442278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S267202
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller