TonEBP recognizes R-loops and initiates m6A RNA methylation for R-loop resolution

R-loops are three-stranded, RNA–DNA hybrid, nucleic acid structures produced due to inappropriate processing of newly transcribed RNA or transcription-replication collision (TRC). Although R-loops are important for many cellular processes, their accumulation causes genomic instability and malignant...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Kang, Hyun Je, Cheon, Na Young, Park, Hyun, Jeong, Gyu Won, Ye, Byeong Jin, Yoo, Eun Jin, Lee, Jun Ho, Hur, Jin-Hoe, Lee, Eun-A, Kim, Hongtae, Lee, Kyoo-young, Choi, Soo Youn, Lee-Kwon, Whaseon, Myung, Kyungjae, Lee, Ja Yil, Kwon, Hyug Moo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797050/
https://ncbi.nlm.nih.gov/pubmed/33313823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1162
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