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TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2

TonEBP is a key transcription factor in cellular adaptation to hypertonic stress, and also in macrophage activation. Since TonEBP is involved in inflammatory diseases such as rheumatoid arthritis and atherosclerosis, we asked whether TonEBP played a role in adipogenesis and insulin resistance. Here...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ho Lee, Jun, Hee Lee, Hwan, Jin Ye, Byeong, Lee-Kwon, Whaseon, Youn Choi, Soo, Moo Kwon, Hyug
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455245/
https://ncbi.nlm.nih.gov/pubmed/26042523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10937
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