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TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2

TonEBP is a key transcription factor in cellular adaptation to hypertonic stress, and also in macrophage activation. Since TonEBP is involved in inflammatory diseases such as rheumatoid arthritis and atherosclerosis, we asked whether TonEBP played a role in adipogenesis and insulin resistance. Here...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Ho Lee, Jun, Hee Lee, Hwan, Jin Ye, Byeong, Lee-Kwon, Whaseon, Youn Choi, Soo, Moo Kwon, Hyug
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455245/
https://ncbi.nlm.nih.gov/pubmed/26042523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10937
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