MiR-CLIP reveals iso-miR selective regulation in the miR-124 targetome

Many microRNAs regulate gene expression via atypical mechanisms, which are difficult to discern using native cross-linking methods. To ascertain the scope of non-canonical miRNA targeting, methods are needed that identify all targets of a given miRNA. We designed a new class of miR-CLIP probe, where...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Wang, Yuluan, Soneson, Charlotte, Malinowska, Anna L, Laski, Artur, Ghosh, Souvik, Kanitz, Alexander, Gebert, Luca F R, Robinson, Mark D, Hall, Jonathan
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Chemical Biology and Nucleic Acid Chemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797034/
https://ncbi.nlm.nih.gov/pubmed/33300035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1117
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