Human Stem Cell-Derived Neurons Repair Circuits and Restore Neural Function

While cell transplantation can rescue motor defects in Parkinson’s disease (PD) models, whether and how grafts functionally repair damaged neural circuitry in the adult brain is not known. We transplanted hESC-derived midbrain dopamine (mDA) or cortical glutamate neurons into the substantia nigra or...

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Publicado en:Cell Stem Cell
Main Authors: Xiong, Man, Tao, Yezheng, Gao, Qinqin, Feng, Ban, Yan, Wei, Zhou, Yingying, Kotsonis, Thomas A., Yuan, Tingli, You, Zhiwen, Wu, Ziyan, Xi, Jiajie, Haberman, Alexander, Graham, Julia, Block, Jasper, Zhou, Wenhao, Chen, Yuejun, Zhang, Su-Chun
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796915/
https://ncbi.nlm.nih.gov/pubmed/32966778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.08.014
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