Required concentration index quantifies effective drug combinations against hepatitis C virus infection

Successful clinical drug development requires rational design of combination treatments based on preclinical data. Anti-hepatitis C virus (HCV) drugs exhibit significant diversity in antiviral effect. Dose-response assessments can be used to determine parameters profiling the diverse antiviral effec...

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Bibliografische gegevens
Gepubliceerd in:Theor Biol Med Model
Hoofdauteurs: Kakizoe, Yusuke, Koizumi, Yoshiki, Ikoma, Yukino, Ohashi, Hirofumi, Wakita, Takaji, Iwami, Shingo, Watashi, Koichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796629/
https://ncbi.nlm.nih.gov/pubmed/33422060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12976-020-00135-6
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