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Quantifying antiviral activity optimizes drug combinations against hepatitis C virus infection

With the introduction of direct-acting antivirals (DAAs), treatment against hepatitis C virus (HCV) has significantly improved. To manage and control this worldwide infectious disease better, the “best” multidrug treatment is demanded based on scientific evidence. However, there is no method availab...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Koizumi, Yoshiki, Ohashi, Hirofumi, Nakajima, Syo, Tanaka, Yasuhito, Wakita, Takaji, Perelson, Alan S., Iwami, Shingo, Watashi, Koichi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338374/
https://ncbi.nlm.nih.gov/pubmed/28174263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610197114
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