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Propofol suppresses microglial phagocytosis through the downregulation of MFG-E8

BACKGROUND: Microglia are highly motile phagocytic cells in the healthy brain with surveillance and clearance functions. Although microglia have been shown to engulf cellular debris following brain insult, less is known about their phagocytic function in the absence of injury. Propofol can inhibit m...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Cai, Xiaoying, Li, Ying, Zheng, Xiaoyang, Hu, Rong, Li, Yingyuan, Xiao, Liangcan, Wang, Zhongxing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796553/
https://ncbi.nlm.nih.gov/pubmed/33422097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02061-3
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