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QSAR Models for Human Carcinogenicity: An Assessment Based on Oral and Inhalation Slope Factors

Carcinogenicity is a crucial endpoint for the safety assessment of chemicals and products. During the last few decades, the development of quantitative structure–activity relationship ((Q)SAR) models has gained importance for regulatory use, in combination with in vitro testing or expert-based reaso...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Toma, Cosimo, Manganaro, Alberto, Raitano, Giuseppa, Marzo, Marco, Gadaleta, Domenico, Baderna, Diego, Roncaglioni, Alessandra, Kramer, Nynke, Benfenati, Emilio
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796303/
https://ncbi.nlm.nih.gov/pubmed/33383938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26010127
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