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Denosumab Discontinuation and the Rebound Phenomenon: A Narrative Review

Denosumab is a potent antiresorptive agent that substantially increases bone mineral density and reduces fracture rates at all skeletal sites for as long as it is administered. However, its favorable skeletal effects reverse quickly upon its discontinuation, because of a vast increase of osteoclast...

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Опубликовано в: :J Clin Med
Главные авторы: Anastasilakis, Athanasios D., Makras, Polyzois, Yavropoulou, Maria P., Tabacco, Gaia, Naciu, Anda Mihaela, Palermo, Andrea
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796169/
https://ncbi.nlm.nih.gov/pubmed/33406802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10010152
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