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Long-term treatment of osteoporosis: safety and efficacy appraisal of denosumab

Denosumab is a fully human monoclonal antibody to the receptor activator of nuclear factor-κB ligand (RANKL), a member of the tumor necrosis factor receptor superfamily essential for osteoclastogenesis. Denosumab treatment is associated with a rapid, sustained, and reversible reduction in bone turno...

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Autors principals: Anastasilakis, Athanasios D, Toulis, Konstantinos A, Polyzos, Stergios A, Anastasilakis, Chrysostomos D, Makras, Polyzois
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387828/
https://ncbi.nlm.nih.gov/pubmed/22767993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S24239
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