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NPM-ALK: A Driver of Lymphoma Pathogenesis and a Therapeutic Target

SIMPLE SUMMARY: Anaplastic lymphoma kinase (ALK) is a tyrosine kinase associated with Anaplastic Large Cell lymphoma (ALCL) through oncogenic translocations mainly NPM-ALK. Chemotherapy is effective in ALK(+) ALCL patients and induces remission rates of approximately 80%. The remaining patients do n...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Andraos, Elissa, Dignac, Joséphine, Meggetto, Fabienne
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795840/
https://ncbi.nlm.nih.gov/pubmed/33466277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13010144
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