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NPM-ALK: A Driver of Lymphoma Pathogenesis and a Therapeutic Target
SIMPLE SUMMARY: Anaplastic lymphoma kinase (ALK) is a tyrosine kinase associated with Anaplastic Large Cell lymphoma (ALCL) through oncogenic translocations mainly NPM-ALK. Chemotherapy is effective in ALK(+) ALCL patients and induces remission rates of approximately 80%. The remaining patients do n...
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| Udgivet i: | Cancers (Basel) |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7795840/ https://ncbi.nlm.nih.gov/pubmed/33466277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13010144 |
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