Curcumin Analogue L48H37 Suppresses Human Osteosarcoma U2OS and MG-63 Cells’ Migration and Invasion in Culture by Inhibition of uPA via the JAK/STAT Signaling Pathway

Osteosarcoma, the most prevalent malignant bone tumor in the pediatric age group, is responsible for the great majority of cancer-associated deaths owing to its highly metastatic potential. The anti-metastatic effects of the new curcumin analogue L48H37 in human osteosarcoma are still unknown; hence...

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Publicado no:Molecules
Main Authors: Lu, Ko-Hsiu, Wu, Heng-Hsiung, Lin, Renn-Chia, Lin, Ya-Chiu, Lu, Peace Wun-Ang, Yang, Shun-Fa, Yang, Jia-Sin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795127/
https://ncbi.nlm.nih.gov/pubmed/33374783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26010030
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