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Mechanisms of Resistance to KRAS(G12C) Inhibitors

SIMPLE SUMMARY: KRAS is a gene that is commonly mutated in cancer, especially in pancreatic, lung and colorectal cancers. Despite its importance, scientists have for many years been unable to create a drug that can inhibit function of the KRAS protein. Recently, several drugs have been created that...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Dunnett-Kane, Victoria, Nicola, Pantelis, Blackhall, Fiona, Lindsay, Colin
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795113/
https://ncbi.nlm.nih.gov/pubmed/33466360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13010151
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