Up-Regulated Expression of Pro-Apoptotic Long Noncoding RNA lincRNA-p21 with Enhanced Cell Apoptosis in Lupus Nephritis

Accelerated cell apoptosis with dysregulated long noncoding RNAs is the crucial pathogenesis in lupus nephritis (LN). Pro-apoptotic lincRNA-p21 was studied in LN patients, cell lines with lentivirus-mediated overexpression and CRISPR interference (CRISPRi)-conducted repression, and a mouse model. Cl...

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Publicado no:Int J Mol Sci
Main Authors: Chen, Yi-Cheng, Kuo, Pin-Yu, Chou, Yu-Chi, Chong, Hao-Earn, Hsieh, Yu-Tung, Yang, Mei-Lin, Wu, Chao-Liang, Shiau, Ai-Li, Wang, Chrong-Reen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795010/
https://ncbi.nlm.nih.gov/pubmed/33396699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010301
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