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Anti-HCMV activity by an irreversible p97 inhibitor LC-1310

The AAA+ (ATPase associated with various cellular activities) protein p97, also called valosin-containing protein, is a hexameric ring ATPase and uses ATP hydrolysis to unfold or extract proteins from biological complexes. Many cellular processes are affected by p97 including ER-associated degradati...

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Bibliografiske detaljer
Udgivet i:Med Chem Res
Main Authors: Wang, Yan, Soto-Acosta, Ruben, Ding, Rui, Chen, Liqiang, Geraghty, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794631/
https://ncbi.nlm.nih.gov/pubmed/33456290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-020-02679-1
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