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High-resolution single-cell 3D-models of chromatin ensembles during Drosophila embryogenesis

Single-cell chromatin studies provide insights into how chromatin structure relates to functions of individual cells. However, balancing high-resolution and genome wide-coverage remains challenging. We describe a computational method for the reconstruction of large 3D-ensembles of single-cell (sc) c...

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Publicat a:Nat Commun
Autors principals: Sun, Qiu, Perez-Rathke, Alan, Czajkowsky, Daniel M., Shao, Zhifeng, Liang, Jie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794469/
https://ncbi.nlm.nih.gov/pubmed/33420075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20490-9
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