Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota

The occurrence and spread of multidrug-resistant pathogens, especially bacteria from the ESKAPE panel, increases the risk to succumb to untreatable infections. We developed a novel antimicrobial peptide, Pam-3, with antibacterial and antibiofilm properties to counter this threat. The peptide is base...

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Dettagli Bibliografici
Pubblicato in:Commun Biol
Autori principali: Koeninger, Louis, Osbelt, Lisa, Berscheid, Anne, Wendler, Judith, Berger, Jürgen, Hipp, Katharina, Lesker, Till R., Pils, Marina C., Malek, Nisar P., Jensen, Benjamin A. H., Brötz-Oesterhelt, Heike, Strowig, Till, Jan Wehkamp
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794397/
https://ncbi.nlm.nih.gov/pubmed/33420317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01582-0
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