EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma

Glioblastoma (GBM) is the most common type of adult malignant brain tumor, but its molecular mechanisms are not well understood. In addition, the knowledge of the disease-associated expression and function of YTHDF2 remains very limited. Here, we show that YTHDF2 overexpression clinically correlates...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Fang, Runping, Chen, Xin, Zhang, Sicong, Shi, Hui, Ye, Youqiong, Shi, Hailing, Zou, Zhongyu, Li, Peng, Guo, Qing, Ma, Li, He, Chuan, Huang, Suyun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794382/
https://ncbi.nlm.nih.gov/pubmed/33420027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20379-7
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