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Restoration of surfactant activity by polymyxin B in lipopolysaccharide-potentiated injury of immature rabbit lungs

During postnatal adaptation pulmonary surfactant may be inactivated by lipopolysaccharide (LPS). We evaluated the effect of surfactant therapy in combination with antibiotic polymyxin B (PxB) in double-hit model of neonatal lung injury. Surfactant (poractant alfa, Curosurf) was exposed to smooth (S)...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Calkovska, Andrea, Haegerstrand-Björkman, Marie, Curstedt, Tore
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794303/
https://ncbi.nlm.nih.gov/pubmed/33420141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79679-z
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