The Intraprostatic Immune Environment after Stereotactic Body Radiotherapy is Dominated by Myeloid Cells

BACKGROUND: Hundreds of ongoing clinical trials combine radiation therapy, mostly delivered as stereotactic body radiotherapy (SBRT), with immune checkpoint blockade. However, our understanding of the effect of radiotherapy on the intratumoral immune balance is inadequate, hindering the optimal desi...

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Publié dans:Prostate Cancer Prostatic Dis
Auteurs principaux: Nickols, Nicholas G., Ganapathy, Ekambaram, Nguyen, Christine, Kane, Nathanael, Lin, Lin, Diaz-Perez, Silvia, Nazarian, Ramin, Mathis, Colleen, Felix, Care, Basehart, Vince, Zomorodian, Nazy, Kwak, Jae, Kishan, Amar U., King, Christopher R., Kupelian, Patrick A., Rettig, Matthew B., Steinberg, Michael L., Cao, Minsong, Knudsen, Beatrice S., Chu, Fang-I, Romero, Tahmineh, Elashoff, David, Reiter, Robert E., Schaue, Dörthe
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794088/
https://ncbi.nlm.nih.gov/pubmed/32647353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-020-0249-8
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