The Intraprostatic Immune Environment after Stereotactic Body Radiotherapy is Dominated by Myeloid Cells

BACKGROUND: Hundreds of ongoing clinical trials combine radiation therapy, mostly delivered as stereotactic body radiotherapy (SBRT), with immune checkpoint blockade. However, our understanding of the effect of radiotherapy on the intratumoral immune balance is inadequate, hindering the optimal desi...

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Detalhes bibliográficos
Publicado no:Prostate Cancer Prostatic Dis
Main Authors: Nickols, Nicholas G., Ganapathy, Ekambaram, Nguyen, Christine, Kane, Nathanael, Lin, Lin, Diaz-Perez, Silvia, Nazarian, Ramin, Mathis, Colleen, Felix, Care, Basehart, Vince, Zomorodian, Nazy, Kwak, Jae, Kishan, Amar U., King, Christopher R., Kupelian, Patrick A., Rettig, Matthew B., Steinberg, Michael L., Cao, Minsong, Knudsen, Beatrice S., Chu, Fang-I, Romero, Tahmineh, Elashoff, David, Reiter, Robert E., Schaue, Dörthe
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794088/
https://ncbi.nlm.nih.gov/pubmed/32647353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-020-0249-8
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