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The axonal sorting activity of pseudorabies virus Us9 protein depends on the state of neuronal maturation

Alpha-herpesviruses establish a life-long infection in the nervous system of the affected host; while this infection is restricted to peripheral neurons in a healthy host, the reactivated virus can spread within the neuronal circuitry, such as to the brain, in compromised individuals and lead to adv...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Tanneti, Nikhila S., Federspiel, Joel D., Cristea, Ileana M., Enquist, Lynn W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794026/
https://ncbi.nlm.nih.gov/pubmed/33370419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008861
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