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Evaluation of CD8 T cell killing models with computer simulations of 2-photon imaging experiments
In vivo imaging of cytotoxic T lymphocyte (CTL) killing activity revealed that infected cells have a higher observed probability of dying after multiple contacts with CTLs. We developed a three-dimensional agent-based model to discriminate different hypotheses about how infected cells get killed bas...
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| Pubblicato in: | PLoS Comput Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7793284/ https://ncbi.nlm.nih.gov/pubmed/33370254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008428 |
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