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Evaluation of CD8 T cell killing models with computer simulations of 2-photon imaging experiments

In vivo imaging of cytotoxic T lymphocyte (CTL) killing activity revealed that infected cells have a higher observed probability of dying after multiple contacts with CTLs. We developed a three-dimensional agent-based model to discriminate different hypotheses about how infected cells get killed bas...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Rastogi, Ananya, Robert, Philippe A., Halle, Stephan, Meyer-Hermann, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793284/
https://ncbi.nlm.nih.gov/pubmed/33370254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008428
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