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Deficiency in Tissue Non-Specific Alkaline Phosphatase Leads to Steatohepatitis in Mice Fed a High Fat Diet Similar to That Produced by a Methionine and Choline Deficient Diet

The liver expresses tissue-nonspecific alkaline phosphatase (TNAP), which may participate in the defense against bacterial components, in cell regulation as part of the purinome or in bile secretion, among other roles. We aimed to study the role of TNAP in the development of hepatosteatosis. TNAP(+/...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gámez-Belmonte, Reyes, Tena-Garitaonaindia, Mireia, Hernández-Chirlaque, Cristina, Córdova, Samir, Ceacero-Heras, Diego, de Medina, Fermín Sánchez, Martínez-Augustin, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793076/
https://ncbi.nlm.nih.gov/pubmed/33374541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010051
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