Dissecting The Genetic Overlap Of Smoking Behaviors, Lung Cancer, And Chronic Obstructive Pulmonary Disease: A Focus On Nicotinic Receptors and Nicotine Metabolizing Enzyme

Smoking is a major contributor to lung cancer and chronic obstructive pulmonary disease (COPD). Two of the strongest genetic associations of smoking-related phenotypes are the chromosomal regions 15q25, encompassing the nicotinic acetylcholine receptor subunit genes CHRNA5-CHRNA3-CHRNB4, and 19q13.2...

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Опубликовано в: :Genet Epidemiol
Главные авторы: Bray, Michael J., Chen, Li-Shiun, Fox, Louis, Hancock, Dana B., Culverhouse, Robert C., Hartz, Sarah M., Johnson, Eric O., Liu, Mengzhen, McKay, James D., Saccone, Nancy L., Hokanson, John E., Vrieze, Scott I., Tyndale, Rachel F., Baker, Timothy B., Bierut, Laura J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793026/
https://ncbi.nlm.nih.gov/pubmed/32803792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22331
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