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Genetic Variant in CHRNA5 and Response to Varenicline and Combination Nicotine Replacement in a randomized placebo-controlled trial

It is unclear if genetic variants affect smoking cessation treatment response. This study tested whether variants in the cholinergic receptor nicotinic alpha 5 subunit (CHRNA5) predict response to smoking cessation medication by directly comparing two most effective smoking cessation pharmacotherapi...

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Dettagli Bibliografici
Pubblicato in:Clin Pharmacol Ther
Autori principali: Chen, Li-Shiun, Baker, Timothy B., Miller, J. Philip, Bray, Michael, Smock, Nina, Chen, Jingling, Stoneking, Faith, Culverhouse, Robert C., Saccone, Nancy L., Amos, Christopher I., Carney, Robert M., Jorenby, Douglas E., Bierut, Laura J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993015/
https://ncbi.nlm.nih.gov/pubmed/32602170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1971
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