The Effect of Chronic Mild Stress and Escitalopram on the Expression and Methylation Levels of Genes Involved in the Oxidative and Nitrosative Stresses as Well as Tryptophan Catabolites Pathway in the Blood and Brain Structures

Previous studies suggest that depression may be associated with reactive oxygen species overproduction and disorders of the tryptophan catabolites pathway. Moreover, one-third of patients do not respond to conventional pharmacotherapy. Therefore, the study investigates the molecular effect of escita...

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Publicado en:Int J Mol Sci
Autores principales: Wigner, Paulina, Synowiec, Ewelina, Jóźwiak, Paweł, Czarny, Piotr, Bijak, Michał, Białek, Katarzyna, Szemraj, Janusz, Gruca, Piotr, Papp, Mariusz, Śliwiński, Tomasz
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792593/
https://ncbi.nlm.nih.gov/pubmed/33374959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010010
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