The Impact of Chronic Mild Stress and Agomelatine Treatment on the Expression Level and Methylation Status of Genes Involved in Tryptophan Catabolic Pathway in PBMCs and Brain Structures

Depression is the serious mental disorder. Previous studies suggest that the development mechanism of depression may be associated with disorders of the tryptophan catabolic pathway (TRYCAT). Thus, this study investigates the effect of agomelatine treatment on the expression and methylation status o...

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Détails bibliographiques
Publié dans:Genes (Basel)
Auteurs principaux: Wigner, Paulina, Synowiec, Ewelina, Jóźwiak, Paweł, Czarny, Piotr, Białek, Katarzyna, Bijak, Michal, Szemraj, Janusz, Gruca, Piotr, Papp, Mariusz, Sliwinski, Tomasz
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563711/
https://ncbi.nlm.nih.gov/pubmed/32962062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11091093
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