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The Impact of Chronic Mild Stress and Agomelatine Treatment on the Expression Level and Methylation Status of Genes Involved in Tryptophan Catabolic Pathway in PBMCs and Brain Structures

Depression is the serious mental disorder. Previous studies suggest that the development mechanism of depression may be associated with disorders of the tryptophan catabolic pathway (TRYCAT). Thus, this study investigates the effect of agomelatine treatment on the expression and methylation status o...

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Bibliografske podrobnosti
izdano v:Genes (Basel)
Main Authors: Wigner, Paulina, Synowiec, Ewelina, Jóźwiak, Paweł, Czarny, Piotr, Białek, Katarzyna, Bijak, Michal, Szemraj, Janusz, Gruca, Piotr, Papp, Mariusz, Sliwinski, Tomasz
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563711/
https://ncbi.nlm.nih.gov/pubmed/32962062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11091093
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