N-acetylcysteine dose-dependently improves the analgesic effect of acetaminophen on the rat hot plate test

BACKGROUND: Acetaminophen (APAP) induced hepatotoxicity is a clinically important problem. Up to now, interventive therapy with n-acetylcysteine (NAC) has been considered as a gold-standard treatment for APAP overdose. However, no study has focused on the efficacy of these drugs’ concurrent administ...

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Detaylı Bibliyografya
Yayımlandı:BMC Pharmacol Toxicol
Asıl Yazarlar: Nakhaee, Samaneh, Dastjerdi, Mohammad, Roumi, Hesam, Mehrpour, Omid, Farrokhfall, Khadijeh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791802/
https://ncbi.nlm.nih.gov/pubmed/33413696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-00469-4
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