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N-acetylcysteine dose-dependently improves the analgesic effect of acetaminophen on the rat hot plate test
BACKGROUND: Acetaminophen (APAP) induced hepatotoxicity is a clinically important problem. Up to now, interventive therapy with n-acetylcysteine (NAC) has been considered as a gold-standard treatment for APAP overdose. However, no study has focused on the efficacy of these drugs’ concurrent administ...
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| Publié dans: | BMC Pharmacol Toxicol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7791802/ https://ncbi.nlm.nih.gov/pubmed/33413696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-00469-4 |
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