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DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair
DNA double-strand breaks (DSBs) are mainly repaired by c-NHEJ and HR pathways. The enhanced DSB mobility after DNA damage is critical for efficient DSB repair. Although microtubule dynamics have been shown to regulate DSB mobility, the reverse effect of DSBs to microtubule dynamics remains elusive....
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| Gepubliceerd in: | J Cell Biol |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Rockefeller University Press
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7791344/ https://ncbi.nlm.nih.gov/pubmed/33404607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201911025 |
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