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Relocation of an extrasynaptic GABA(A) receptor to inhibitory synapses freezes excitatory synaptic strength and preserves memory
The excitatory synapse between hippocampal CA3 and CA1 pyramidal neurons exhibits long-term potentiation (LTP), a positive feedback process implicated in learning and memory, in which postsynaptic depolarization strengthens synapses, promoting further depolarization. Without mechanisms for interrupt...
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| Publicado no: | Neuron |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7790995/ https://ncbi.nlm.nih.gov/pubmed/33096025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2020.09.037 |
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