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Cyclic peptides: Backbone rigidification and capability of mimicking motifs at protein–protein interfaces
Cyclization is commonly employed in efforts to improve the target binding affinity of peptide-based probes and therapeutics. Many structural motifs have been identified at protein–protein interfaces and provide promising targets for inhibitor design using cyclic peptides. Cyclized peptides are gener...
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| Publicat a: | Phys Chem Chem Phys |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7790991/ https://ncbi.nlm.nih.gov/pubmed/33331371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cp04633g |
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