Adrenergic Ca(V)1.2 Activation via Rad Phosphorylation Converges at α(1C) I-II Loop

RATIONALE: Changing activity of cardiac Ca(V)1.2 channels under basal conditions, during sympathetic activation, and in heart failure is a major determinant of cardiac physiology and pathophysiology. Although cardiac Ca(V)1.2 channels are prominently up-regulated via activation of protein kinase A,...

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Veröffentlicht in:Circ Res
Hauptverfasser: Papa, Arianne, Kushner, Jared, Hennessey, Jessica A., Katchman, Alexander N., Zakharov, Sergey I., Chen, Bi-xing, Yang, Lin, Lu, Ree, Leong, Stephen, Diaz, Johanna, Liu, Guoxia, Roybal, Daniel, Liao, Xianghai, del Rivero Morfin, Pedro J., Colecraft, Henry M., Pitt, Geoffrey S., Clarke, Oliver, Topkara, Veli, Ben-Johny, Manu, Marx, Steven O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790865/
https://ncbi.nlm.nih.gov/pubmed/33086983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.317839
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