Whole exome and transcriptome analysis of UV-exposed epidermis and carcinoma in situ reveals early drivers of carcinogenesis

Squamous cell carcinoma in situ (SCCIS) is a prevalent precancerous lesion that can progress to cutaneous squamous cell carcinoma (cSCC). Although SCCIS is common, its pathogenesis remains poorly understood. To better understand SCCIS development, we performed laser-captured microdissection of human...

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Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Zheng, Qi, Capell, Brain, Parekh, Vishwas, O’Day, Conor, Atillasoy, Cem, Bashir, Hasan M., Yeh, Christopher, Shim, Eun-Hee, Prouty, Stephen M., Dentchev, Tzvete, Lee, Vivian, Wushanley, Lily, Kweon, Yerin, Suzuki-Horiuchi, Yoko, Pear, Warren, Grice, Elizabeth A., Seykora, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790860/
https://ncbi.nlm.nih.gov/pubmed/32649944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.05.116
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