p15 Expression Differentiates Nevus from Melanoma

Most melanomas are driven by BRAF(V600E)-activating mutations, while nevi harboring the same mutations have growth arrest. Although decreased p16 expression has been associated with melanoma formation, in recent work, p15 represented a primary effector of oncogene-induced senescence in nevomelanocyt...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Taylor, Laura A., O'Day, Conor, Dentchev, Tzvete, Hood, Kyle, Chu, Emily Y., Ridky, Todd W., Seykora, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225287/
https://ncbi.nlm.nih.gov/pubmed/27855847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.08.009
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