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p15 Expression Differentiates Nevus from Melanoma
Most melanomas are driven by BRAF(V600E)-activating mutations, while nevi harboring the same mutations have growth arrest. Although decreased p16 expression has been associated with melanoma formation, in recent work, p15 represented a primary effector of oncogene-induced senescence in nevomelanocyt...
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| Publicado en: | Am J Pathol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Investigative Pathology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225287/ https://ncbi.nlm.nih.gov/pubmed/27855847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.08.009 |
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