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CDKN2B loss promotes progression from benign melanocytic nevus to melanoma
Deletion of the entire CDKN2B-CDKN2A gene cluster is among the most common genetic events in cancer. The tumor-promoting effects are generally attributed to loss of CDKN2A-encoded p16 and p14ARF tumor suppressors. The degree to which the associated CDKN2B-encoded p15 loss contributes to human tumori...
में बचाया:
| में प्रकाशित: | Cancer Discov |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592422/ https://ncbi.nlm.nih.gov/pubmed/26183406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0196 |
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