Microbiota-dependent expansion of testicular IL-17-producing Vγ6(+) γδ T cells upon puberty promotes local tissue immune surveillance

γδT cells represent the majority of lymphocytes in several mucosal tissues where they contribute to tissue homoeostasis, microbial defence and wound repair. Here we characterise a population of interleukin (IL) 17-producing γδ (γδ17) T cells that seed the testis of naive C57BL/6 mice, expand at pube...

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Udgivet i:Mucosal Immunol
Main Authors: Wilharm, Anneke, Brigas, Helena C., Sandrock, Inga, Ribeiro, Miguel, Amado, Tiago, Reinhardt, Annika, Demera, Abdi, Hoenicke, Lisa, Strowig, Till, Carvalho, Tânia, Prinz, Immo, Ribot, Julie C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790758/
https://ncbi.nlm.nih.gov/pubmed/32733025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-0330-6
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