IL-17C contributes to NTHi-induced inflammation and lung damage in experimental COPD and is present in sputum during acute exacerbations

Neutrophilic inflammation results in loss of lung function in chronic obstructive pulmonary disease (COPD). Gram-negative bacteria, such as nontypeable Haemophilus influenzae (NTHi), trigger acute exacerbations of COPD (AECOPD) and contribute to chronic lung inflammation. The pro-inflammatory cytoki...

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Udgivet i:PLoS One
Main Authors: Vella, Giovanna, Ritzmann, Felix, Wolf, Lisa, Kamyschnikov, Andreas, Stodden, Hannah, Herr, Christian, Slevogt, Hortense, Bals, Robert, Beisswenger, Christoph
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790230/
https://ncbi.nlm.nih.gov/pubmed/33411748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243484
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