IL-17C contributes to NTHi-induced inflammation and lung damage in experimental COPD and is present in sputum during acute exacerbations

Neutrophilic inflammation results in loss of lung function in chronic obstructive pulmonary disease (COPD). Gram-negative bacteria, such as nontypeable Haemophilus influenzae (NTHi), trigger acute exacerbations of COPD (AECOPD) and contribute to chronic lung inflammation. The pro-inflammatory cytoki...

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Publicat a:PLoS One
Autors principals: Vella, Giovanna, Ritzmann, Felix, Wolf, Lisa, Kamyschnikov, Andreas, Stodden, Hannah, Herr, Christian, Slevogt, Hortense, Bals, Robert, Beisswenger, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790230/
https://ncbi.nlm.nih.gov/pubmed/33411748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243484
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