Single-Cell Profiling of AKI in a Murine Model Reveals Novel Transcriptional Signatures, Profibrotic Phenotype, and Epithelial-to-Stromal Crosstalk

BACKGROUND: Current management of AKI, a potentially fatal disorder that can also initiate or exacerbate CKD, is merely supportive. Therefore, deeper understanding of the molecular pathways perturbed in AKI is needed to identify targets with potential to lead to improved treatment. METHODS: We perfo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Rudman-Melnick, Valeria, Adam, Mike, Potter, Andrew, Chokshi, Saagar M., Ma, Qing, Drake, Keri A., Schuh, Meredith P., Kofron, J. Matthew, Devarajan, Prasad, Potter, S. Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790221/
https://ncbi.nlm.nih.gov/pubmed/33115917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020010052
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados