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Syncytium cell growth increases Kir2.1 contribution in human iPSC-cardiomyocytes

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) enable cardiotoxicity testing and personalized medicine. However, their maturity is of concern, including relatively depolarized resting membrane potential and more spontaneous activity compared with adult cardiomyocytes, implica...

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Bibliographic Details
Published in:Am J Physiol Heart Circ Physiol
Main Authors: Li, Weizhen, Han, Julie L., Entcheva, Emilia
Format: Artigo
Language:Inglês
Published: American Physiological Society 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789971/
https://ncbi.nlm.nih.gov/pubmed/32986966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00148.2020
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