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Syncytium cell growth increases Kir2.1 contribution in human iPSC-cardiomyocytes
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) enable cardiotoxicity testing and personalized medicine. However, their maturity is of concern, including relatively depolarized resting membrane potential and more spontaneous activity compared with adult cardiomyocytes, implica...
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| Veröffentlicht in: | Am J Physiol Heart Circ Physiol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7789971/ https://ncbi.nlm.nih.gov/pubmed/32986966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00148.2020 |
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